| Registro completo |
| Provedor de dados: |
ArchiMer
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| País: |
France
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| Título: |
Expression of immune-related genes in the oyster Crassostrea gigas during ontogenesis
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| Autores: |
Tirape, Ana
Bacque, Coralie
Brizard, Raphael
Vandenbulcke, Franck
Boulo, Viviane
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| Data: |
2007-07
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| Ano: |
2007
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| Palavras-chave: |
Rel/NF kappa B pathway
Cell proliferation
Hematopoiesis
Mollusk immunity
Hemocytes
Bivalve mollusk
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| Resumo: |
The work presented here reports the expression of immune-related genes during ontogenesis in the oyster Crassostrea gigar. Expression patterns of 18 selected genes showed that RNAs detected in oocytes and 2-4 cell embryos are of maternal origin and that gene transcription starts early after fertilization. The expression patterns of 4 genes (Cg-timp, Cg-tal, Cg-EcSOD and Drac3) suggested that hemocytes appear in the gastrula-trochophore stages. The localization of Cg-tal expression suggested that hematopoietic cells were derived from vessels and/or artery endothelia cells. Moreover, a bacterial challenge affected the level of expression of genes. Indeed, a change in expression levels was observed for Cg-LBP/BPI, Cg-timp, Drac3 and Cg-MyD88 genes in larval stages upon exposure to non-pathogenic bacteria. In early juveniles, a modulation was also observed for Cg-LBP/BPI, Cg-timp, Cg-MyD88 and for Cg-tal, according to the concentration of bacteria. Altogether, the results showed that studying the appearance of immunocompetent cells through their ability to express immune-related genes is a tool to gain insight the ontogenesis of the oyster immune system. (C) 2007 Elsevier Ltd. All rights reserved.
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| Tipo: |
Text
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| Idioma: |
Inglês
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| Identificador: |
http://archimer.ifremer.fr/doc/2007/publication-2612.pdf
DOI:10.1016/j.dci.2007.01.005
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| Editor: |
Elsevier
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| Relação: |
http://archimer.ifremer.fr/doc/00000/2612/
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| Formato: |
application/pdf
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| Fonte: |
Developmental & Comparative Immunology (0145-305X) (Elsevier), 2007-07 , Vol. 31 , N. 9 , P. 859-873
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| Direitos: |
2007 Elsevier Ltd All rights reserved.
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